常用名 | Prexasertib甲磺酸盐水合物 | CAS号 | 1234015-57-6 |
---|---|---|---|
价格 | $需询单/250mg $需询单/100mg $需询单/1g | 纯度 | 98.0% |
备货期 | 3天 | 库存 | 3 |
产品网页 | https://www.dcchemicals.com/product_show-Prexasertib_Mesylate_Hydrate.html |
产品详情(用途,包装等)
Prexasertib Mesylate Hydrate (LY2606368 Mesylate Hydrate) is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. Prexasertib Mesylate Hydrate inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM). Prexasertib Mesylate Hydrate causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis. Prexasertib Mesylate Hydrate shows potent anti-tumor activity. |