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别嘌醇

更新时间:2025-08-28 12:49:24

常用名 别嘌醇 CAS号 315-30-0
价格 ¥150.0/1kg 纯度 99.5%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Allopurinol (Zyloprim) is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.Target: XAOAllopurinol (Zyloprim, and generics) is a drug used primarily to treat hyperuricemia (excess uric acid in blood plasma) and its complications, including chronic gout. It is a xanthine oxidase inhibitor which is administered orally. A common misconception is that allopurinol is metabolized by its target, xanthine oxidase, but this action is principally carried out by Aldehyde oxidase. The active metabolite of allopurinol is oxypurinol, which is also an inhibitor of xanthine oxidase. Allopurinol is almost completely metabolized to oxypurinol within two hours of oral administration, whereas oxypurinol is slowly excreted by the kidneys over 18–30 hours. For this reason, oxypurinol is believed responsible for the majority of allopurinol's effect.Allopurinol is a purine analog; it is a structural isomer of hypoxanthine (a naturally occurring purine in the body) and is an inhibitor of the enzyme xanthine oxidase. In addition to blocking uric acid production, inhibition of xanthine oxidase causes an increase in hypoxanthine and xanthine. While xanthine cannot be converted to purine ribotides, hypoxanthine can be salvaged to the purine ribotides adenosine and guanosine monophosphates. Increased levels of these ribotides may cause feedback inhibition of amidophosphoribosyl transferase, the first and rate-limiting enzyme of purine biosynthesis. Allopurinol, therefore, decreases uric acid formation and may also inhibit purine synthesis.
物理化学性质:
CAS号:315-30-0
常用中文名:别嘌醇
常用英文名:Allopurinol
分子式:C5H4N4O
分子量:136.111
密度:1.7±0.1 g/cm3
沸点:290.8ºC at 760 mmHg
熔点:350 ºC
闪点:129.7ºC
储存条件:库房低温,通风,干燥,与食品原料分开存放

供应商信息

上海富蔗化工有限公司

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电话:021-66402541
地址:汶水路301号
地区: 上海市 上海市 静安区
联系人:魏女士
联系人电话:021-66402541 66402542 13901914741
邮件:2308653804@qq.com
网址:http://www.fuzhechem.com/
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参考价格:¥47/10g
其他供应商价格:
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2018-05-10 阿罗嘌呤
价格:¥260.0
2023-11-02 别嘌醇
价格:¥需询单
2021-02-06 Allopurinol
价格:¥869.0
2017-11-30 别嘌醇
价格:¥需询单

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