| 常用名 | 马来酸桂哌齐特 | CAS号 | 26328-04-1 |
|---|---|---|---|
| 价格 | ¥需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 7天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Cinepazide Maleate is a vasodilator.Target: OthersCinepazide maleate is a maleate salt form of cinepazide which is a vasodilator. Cinepazide (30 mg/kg, i.v.) potentiated the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, Intravertebral cinepazide(1-10 mg) increased vertebral blood flow in a dose-related manner and the effect was partially inhibited by intravenous pretreatment with aminophylline but not by pretreatment with autonomic antagonists. Cinepazide resembled cinnarizine and papaverine in that the drug antagonized rabbit aortic contraction induced by KCl, norepinephrine or CaCl2 [1]. Cinepazide in concentrations ranging from 10-6 to 10-5M augmented the relaxing responses to ATP, adenosine and cAMP. However, this agent did not affect the relaxations induced by isoproterenol and papaverine and the contractions induced by 5-HT, prostaglandin F2α and ATP. cinepazide selectively potentiates the relaxing response mediated through purinergic P1 receptors [2]. 物理化学性质: CAS号:26328-04-1 常用中文名:马来酸桂哌齐特 常用英文名:Cinepazide maleate 分子式:C26H35N3O9 分子量:533.57100 密度:1.256 沸点:637.8ºC at 760 mmHg 熔点:173 °C(dec.) 闪点:339.5ºC 储存条件:-20°C |