FTI 277 HYDROCHLORIDE
更新时间：2023-10-17 18:34:33
采购访问：38次
| 常用名 | FTI-277盐酸盐 | CAS号 | 180977-34-8 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： FTI-277 Hcl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.IC50 value:Target: FTase inhibitorin vitro: Treatment with FTI-277 (20 microM) for 48 h prior to irradiation led to a significant decrease in survival of radioresistant cells expressing the 24-kDa isoform (HeLa 3A) but had no effect on the survival of control cells (HeLa PINA). The radiosensitizing effect of FTI-277 is accompanied by a stimulation of postmitotic cell death in HeLa 3A cells and by a reduction in G(2)/M-phase arrest in both cell types [1]. Treatment of PC-3 cells with GGTI-298 and FTI-277 inhibited migration and invasion in a time- and dose-dependent manner [3].in vivo: FTI-277 treatment prevented increased PTP-1B and PTEN protein expression in burned mice as compared with vehicle alone. In contrast, FTI-277 did not significantly alter protein expression of PTP-1B and PTEN in sham-burned mice [2]. 物理化学性质： CAS号：180977-34-8 常用中文名：FTI-277盐酸盐 常用英文名：FTI-277 (hydrochloride) 分子式：C22H30ClN3O3S2 分子量：484.07500 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：−20°C |
达阳化工（杭州）有限公司
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：FTI 277 盐酸盐
- 价格： ￥792.9/5mg ￥1089.9/1ml ￥4531.9/100mg ￥1184.9/10mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$145/10mM*1mLinDMSO