L-Glutamic acid,N-[4-[[(2,4-diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-
更新时间：2021-07-26 18:31:53
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| 常用名 | 氨甲叶酸7-羟基代谢物 | CAS号 | 5939-37-7 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： 7-Hydroxymethotrexate is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases. Elimination of 7-hydroxy MTX is associated with the multi-drug transporters Abcc2, Abcc3, and Abcg2 in transgenic mouse models. It and the parent compound rapidly accumulate when all three transporters are absent.2 Formulations containing methotrexate have been used in the treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. Various methods have been described to quantify 7-hydroxy MTX levels during cancer therapy to avoid toxicity. 物理化学性质： CAS号：5939-37-7 常用中文名：氨甲叶酸7-羟基代谢物 常用英文名：7-Hydroxymethotrexate 分子式：C20H22N8O6 分子量：470.43900 密度：1.68g/cm3 沸点：N/A 熔点：230ºC dec. 闪点：N/A 储存条件：-20°C，密闭，干燥 |
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