| 常用名 | 依碳氯替泼诺 | CAS号 | 82034-46-6 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Loteprednol Etabonate is an anti-inflammatory corticosteroid used in optometry and ophthalmology.IC50 Value:Target: Glucocorticoid Receptorin vitro:in vivo: Intravenous administration of loteprednol etabonate (5 mg/kg) to dogs revealed a terminal half-life of 2.8 h, a volume of distribution of 3.7 L/kg, and a total body clearance of 0.9 L/h/kg. Intact loteprednol etabonate was not detectable in the urine. After oral administration of the drug (5 mg/kg) to dogs, only metabolites, but no intact drug, were found in the plasma, an indication for a high first-pass effect. A pronounced binding of the drug to plasma protein (> 90%) and a high erythrocyte-buffer partition coefficient of 7.8 were determined in vitro. 物理化学性质: CAS号:82034-46-6 常用中文名:依碳氯替泼诺 常用英文名:Loteprednol etabonate 分子式:C24H31ClO7 分子量:466.952 密度:1.3±0.1 g/cm3 沸点:600.1±55.0 °C at 760 mmHg 熔点:220.5-223.5ºC 闪点:316.7±31.5 °C 储存条件:-20°C Freezer |