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Balicatib

更新时间:2025-08-08 17:34:02 采购访问:19次

常用名 巴利卡替 CAS号 354813-19-7
价格 $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Balicatib(AAE-581) is a potent and selective inhibitor of cathepsin K; 10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.IC50 value:Target: cathepsin KThe cathepsin K inhibitor AAE-581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005. Eighty adult female Macaca fascicularis underwent bilateral ovariectomies and were dosed twice daily by oral gavage with balicatib at 0, 3, 10, and 50 mg/kg for 18 months (groups O, L, M, H, respectively). Approximately 1 month after treatment initiation, the 50 mg/kg dose was decreased to 30 mg/kg. Twenty animals underwent sham-ovariectomies (group S). Bone mass was measured at 3-6 month intervals. At 18 months, vertebra and femur were collected for histomorphometry.
物理化学性质:
CAS号:354813-19-7
常用中文名:巴利卡替
常用英文名:Balicatib
分子式:C23H33N5O2
分子量:411.540
密度:1.2±0.1 g/cm3
沸点:687.4±55.0 °C at 760 mmHg
熔点:N/A
闪点:369.5±31.5 °C
储存条件:-20℃

供应商信息

达阳化工(杭州)有限公司 认证供应商

认证状态:已认证供应商
商品数:50181件
电话:+86571-88938639
地址:浙江省杭州市西湖区文三路259号2栋9楼
地区: 浙江省 杭州市 西湖区
联系人:王小姐
联系人电话:+86-571-8893-8639
邮件:enquiry@dycnchem.com
网址:http://www.dycnchem.com
主要市场:Mainly in Southeast Asia and European and American markets
年贸易额:10 to 20 million USD
外贸占销售比例:90%
主要合作伙伴:
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参考价格:$145/10mM*1mLinDMSO
其他供应商价格:
2022-02-19 Balicatib
价格:¥3072.9
2023-09-11 Balicatib
价格:¥需询单
2021-02-06 Balicatib
价格:¥1089.0
2017-09-05 Balicatib
价格:¥需询单

查看所有价格,请点击巴利卡替价格