| 常用名 | Sonolisib | CAS号 | 502632-66-8 |
|---|---|---|---|
| 价格 | $需询单/100g $需询单/1kg $需询单/100kg $需询单/1000kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Sonolisib, also known as PX-866, is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and delta isoforms of phosphoinositide 3-kinase (PI3K) with potential antineoplastic activity. PI3K inhibitor PX-866 inhibits the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of the PI3K/Akt signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. 物理化学性质: CAS号:502632-66-8 常用中文名:Sonolisib 常用英文名:PX-866 分子式:C29H35NO8 分子量:525.590 密度:1.3±0.1 g/cm3 沸点:651.4±55.0 °C at 760 mmHg 熔点:N/A 闪点:347.7±31.5 °C 储存条件:-20°C,干燥,密封 |