(1R)-2,3-dihydro-N-2-propyn-1-yl-1H-inden-1-amine
更新时间：2025-11-16 13:52:16
| 常用名 | 雷沙吉兰 | CAS号 | 136236-51-6 |
|---|---|---|---|
| 价格 | $需询单/1kg $需询单/5kg $需询单/50kg $需询单/500g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品网页 | https://saflikpharma.com/?page_id=74 | ||
| 产品详情（用途，包装等）
用途： Rasagiline(AGN1135;TVP1012) is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease. Target: Monoamine Oxidase (MAO)-BRasagiline (N-propargyl-1-(R)-aminoindan) is a novel, highly potent irreversible monoamine oxidase (MAO)-B inhibitor, anti-Parkinsonian drug. Rasagiline is effective as monotherapy or adjunct to L-Dopa for patients with early and late Parkinson's disease (PD) [1]. Rasagiline inhibits MAO-B more potently than selegiline and has the advantage of once-daily dosing. In several large, randomized, placebo-controlled trials, rasagiline has demonstrated efficacy as monotherapy in early PD and as adjunctive therapy in advanced PD. In addition, rasagiline has been shown to have neuroprotective effects in in vitro and in vivo studies. The recently completed delayed-start ADAGIO (Attenuation of Disease Progression with Azilect Given Once-daily) trial suggests a potential disease-modifying effect for rasagiline 1 mg/day, though the clinical import of this finding has yet to be established [2]. Rasagiline has been found to be well tolerated and effective in the treatment of early PD and as adjunctive treatment in motor fluctuations. Whether rasagiline is associated with clinically significant neuroprotection (ie, disease modification) in PD is the subject of ongoing clinical trials [3]. 物理化学性质： CAS号：136236-51-6 常用中文名：雷沙吉兰 常用英文名：Rasagiline 分子式：C12H13N 分子量：171.238 密度：1.1±0.1 g/cm3 沸点：305.5±30.0 °C at 760 mmHg 熔点：35-41°C 闪点：146.8±20.0 °C 储存条件：2-8°C |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：雷沙吉兰
- 价格： ￥123.9/100mg ￥617.9/1g ￥222.9/250mg ￥205.9/1ml
- 纯度：97.0%
- 备货期：1天
- 联系人：阿拉丁
- 盼得（上海）国际贸易有限公司
- 上海市 上海市 徐汇区
- 产品名：雷沙吉兰（游离碱）
- 价格： ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：需询单
- 联系人：叶经理
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参考价格：￥493.2/1g