| 常用名 | 盐酸氮卓斯汀 | CAS号 | 79307-93-0 |
|---|---|---|---|
| 价格 | ¥需询单/1kg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Azelastine HCl is a potent, second-generation, selective, histamine antagonist.Target: Histamine ReceptorAzelastine is a selective H(1)-receptor antagonist that inhibits histamine release and interferes with activation of several other mediators of allergic inflammation. Azelastine can inhibit CHMCs activation and release of IL-6, tryptase, and histamine. On an equimolar basis, azelastine was a more potent inhibitor than olopatadine [1]. Topical azelastine progressively improved itching and conjunctival redness in PAC patients compared to placebo and was at least as effective as levocabastine. Rapid relief is consistent with H(1)-receptor antagonist action, while continued improvement up to 6 weeks may be consistent with mechanisms involving other mediators of allergic inflammation [2]. Azelastine nasal spray was reported to control all rhinitis symptoms, including nasal congestion, regardless of rhinitis diagnosis during the 2-week study period. Patients with seasonal allergic rhinitis and patients with seasonal allergic rhinitis plus nonallergic triggers were identified as patient types most likely to respond to azelastine nasal spray [3]. 物理化学性质: CAS号:79307-93-0 常用中文名:盐酸氮卓斯汀 常用英文名:azelastine hydrochloride 分子式:C22H25Cl2N3O 分子量:418.359 密度:1.25 g/cm3 沸点:533.9ºC at 760 mmHg 熔点:225-229ºC 闪点:276.7ºC 储存条件:通风低温干燥,与库房食品原料分开存放 |