| 常用名 | KN-92 盐酸盐 | CAS号 | 1431698-47-3 |
|---|---|---|---|
| 价格 | ¥需询单/1g ¥需询单/5g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: KN-92 is an inactive derivative of KN-93. KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). IC50 value:Target: KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell. 物理化学性质: CAS号:1431698-47-3 常用中文名:KN-92 盐酸盐 常用英文名:KN-92-hydrochloride 分子式:C24H26Cl2N2O3S 分子量:493.45 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:2-8℃ |