TGR5
更新时间：2023-09-11 10:56:02
| 常用名 | 3-(2-氯苯基)-n-(4-氯苯基)-n,5-二甲基-4-异噁唑羧酰胺 | CAS号 | 1197300-24-5 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： TGR5 Receptor Agonist, a potent TGR5(GPCR19) agonist, showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5).IC50 value: 6.8 (pEC50, U2-OS cell assay); 7.5(pEC50, melanophore cell) [1]Target: TGR5TGR5 Receptor Agonist was profiled against more than 100 in-house and external 7TM, ion channel, enzyme, transporter, and nuclear hormone receptor selectivity assays, including FXR, another bile acid receptor, and showed significant response only in secretion of the pro-inflammatory cytokine TNFalpha (pIC50 = 6.8) in human primary monocytes following stimulation with LPS (lipopolysaccharide). In addition, TGR5 Receptor Agonist has good physicochemical properties and no measurable activity against three of the common cytochrome P450 (CYP450) isoforms (1A2, 2C9, and 2D6) or hERG dofetilide binding (pIC50 物理化学性质： CAS号：1197300-24-5 常用中文名：3-(2-氯苯基)-n-(4-氯苯基)-n,5-二甲基-4-异噁唑羧酰胺 常用英文名：TGR5 分子式：C18H14Cl2N2O2 分子量：361.222 密度：1.3±0.1 g/cm3 沸点：541.8±50.0 °C at 760 mmHg 熔点：N/A 闪点：281.5±30.1 °C 储存条件：-20℃ |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：TGR5受体激动剂
- 价格： ￥926.9/10mg ￥555.9/5mg ￥2100.9/25mg ￥3274.9/50mg
- 纯度：99.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：TGR5
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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3-(2-氯苯基)-n-(4-氯苯基)-n,5-二甲基-4-异噁唑羧酰胺生产厂家
参考价格：$370/10mM*1mLinDMSO