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Balicatib

更新时间:2023-09-11 17:08:05

常用名 巴利卡替 CAS号 354813-19-7
价格 ¥需询单/1kg ¥需询单/1g ¥需询单/1mg 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Balicatib(AAE-581) is a potent and selective inhibitor of cathepsin K; 10-100 fold more potent in cell-based enzyme occupancy assays than against cathepsin B, L, and S.IC50 value:Target: cathepsin KThe cathepsin K inhibitor AAE-581 (balicatib) as the most advanced of them passed Phase II clinical trials in 2005. Eighty adult female Macaca fascicularis underwent bilateral ovariectomies and were dosed twice daily by oral gavage with balicatib at 0, 3, 10, and 50 mg/kg for 18 months (groups O, L, M, H, respectively). Approximately 1 month after treatment initiation, the 50 mg/kg dose was decreased to 30 mg/kg. Twenty animals underwent sham-ovariectomies (group S). Bone mass was measured at 3-6 month intervals. At 18 months, vertebra and femur were collected for histomorphometry.
物理化学性质:
CAS号:354813-19-7
常用中文名:巴利卡替
常用英文名:Balicatib
分子式:C23H33N5O2
分子量:411.540
密度:1.2±0.1 g/cm3
沸点:687.4±55.0 °C at 760 mmHg
熔点:N/A
闪点:369.5±31.5 °C
储存条件:-20℃

供应商信息

上海楼岚生物科技有限公司

认证状态:未认证供应商
电话:52996696
地址:沪南路2729弄1310号
地区: 上海市 上海市 浦东新区
联系人:孙先生
联系人电话:021-52996696
邮件:sales@lollanechem.com
网址:http://www.bioll.com
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参考价格:$145/10mM*1mLinDMSO
其他供应商价格:
2022-11-29 Balicatib
价格:¥需询单
2021-02-06 Balicatib
价格:¥1089.0
2022-02-19 Balicatib
价格:¥3072.9
2017-09-05 Balicatib
价格:¥需询单

查看所有价格,请点击巴利卡替价格