Gemcitabine elaidate
更新时间：2024-09-30 11:09:46
| 常用名 | 吉西他滨反油酸酯 | CAS号 | 210829-30-4 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Gemcitabine elaidate(CP-4126; CO-101) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity.IC50 value:Target: Gemcitabine analogUpon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Check for active clinical trials or closed clinical trials using this agent. 物理化学性质： CAS号：210829-30-4 常用中文名：吉西他滨反油酸酯 常用英文名：Gemcitabine elaidate 分子式：C27H43F2N3O5 分子量：527.644 密度：1.2±0.1 g/cm3 沸点：631.4±65.0 °C at 760 mmHg 熔点：N/A 闪点：335.7±34.3 °C 储存条件：2-8℃ |
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Gemcitabine elaidate
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：Gemcitabine elaidate
- 价格： ￥6680.9/100mg ￥4450.9/50mg ￥1050.9/5mg ￥342.9/1mg
- 纯度：99.0%
- 备货期：10天
- 联系人：阿拉丁
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：Gemcitabine elaidate
- 价格： ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：周经理
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参考价格：$146/10mM*1mLinDMSO