LY2365109 HCl
更新时间：2024-01-12 13:51:19
| 常用名 | LY2365109盐酸盐 | CAS号 | 1779796-27-8 |
|---|---|---|---|
| 价格 | ￥需询单/1g ￥需询单/1mg | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： LY2365109 is a potent and selective GlyT1 inhibitors with IC50 value of 15.8 nM.target: GlyT1[1]IC 50: 15.8 nM [1]In vivo: The reference for LY2365109 is 0.3 or 30 mg/kg by PO. LY2365109 appeared slightly more potent than ALX5407 over the dose-range tested on CSF levels of glycine in the ratLY2365109 can act to potentiate NMDA function in the PFC but also mediate sustained inhibition of GlyT1 transporters in caudal areas of the brain.[1] LY2365109 increased seizure thresholds in mice. Importantly, chronic seizures in the mouse model of TLE were robustly suppressed by systemic administration of the GlyT1 inhibitor LY2365109. [2] 物理化学性质： CAS号：1779796-27-8 常用中文名：LY2365109盐酸盐 常用英文名：LY 2365109 hydrochloride 分子式：C22H28ClNO5 分子量：421.914 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：2-8℃ |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：LY 2365109 hydrochloride
- 价格： ￥753.9/5mg ￥5397.9/100mg ￥1318.9/10mg ￥2471.9/25mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$132/10mM*1mLinDMSO