| 常用名 | 甲基泼尼松 | CAS号 | 1247-42-3 |
|---|---|---|---|
| 价格 | ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Meprednisone is a glucocorticoid and a methylated derivative of prednisone.Target: Glucocorticoid ReceptorMeprednisone is a glucocorticoid and a methylated derivative of prednisone. The methylprednisone to MPL area under the curve ratio decreased from 0.19 +/- 0.04 in control to 0.14 +/- 0.03 in ketoconazole-treated rats (P less than .05) due to altered interconversion between these steroids. An improved pharmacokinetic/dynamic receptor/gene-mediated model characterized the steroid receptor binding and induction of tyrosine aminotransferase activity after i.v. MPL sodium succinate (10 mg/kg). In contrast to previous in vitro studies, ketoconazole at maximally tolerated doses failed to antagonize the steroid receptor-mediated activity of MPL [1]. 物理化学性质: CAS号:1247-42-3 常用中文名:甲基泼尼松 常用英文名:meprednisone 分子式:C22H28O5 分子量:372.455 密度:1.3±0.1 g/cm3 沸点:574.4±50.0 °C at 760 mmHg 熔点:204-206ºC 闪点:315.2±26.6 °C 储存条件:2~8°C |