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更新时间:2024-02-05 16:40:34

常用名 瑞来巴坦 CAS号 1174018-99-5
价格 ¥需询单/1kg ¥需询单/100g ¥需询单/1ton 纯度 99.0%
备货期 需询单 库存 现货
 产品详情(用途,包装等)
用途:
Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases [ESBLs] and KPC) and class C (AmpC) enzymes.Target: beta-lactamaseImipenem with Relebactam is active against Escherichia coli, Klebsiella pneumoniae, and Enterobacter spp., including K. pneumoniae carbapenemase (KPC)-producing isolates. The combination of Imipenem with Relebactam demonstrated activity against KPC-producing Enterobacteriaceae and multidrug-resistant P. aeruginosa. The imipenem MIC50 and MIC90 values for the ESBL-producing isolates were 0.25 and 0.5 μg/ml, respectively; with the addition of Relebactam, the corresponding values were 0.25 and 0.25 μg/ml. Five isolates harbored blaKPC. For these 5 isolates, the imipenem MICs ranged from 0.5 to >32 μg/ml. With the addition of Relebactam, the MICs decreased to 0.12 to 0.5 μg/ml.[1] Relebactam inhibits most class A and class C β-lactamases, with selected inhibition of class D enzymes by avibactam. β-Lactamase inhibitors (BLIs) have played an important role in combatting β-lactam resistance in Gram-negative bacteria, but their effectiveness has diminished with the evolution of diverse and deleterious varieties of β-lactamases.[2]
物理化学性质:
CAS号:1174018-99-5
常用中文名:瑞来巴坦
常用英文名:Relebactam
分子式:C12H20N4O6S
分子量:348.37500
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A
储存条件:2-8℃

供应商信息

和鼎(南京)医药技术有限公司

认证状态:未认证供应商
电话:025-58467899-8094
地址:江苏·南京江北新区探秘路73号树屋十六栋A-3栋
地区: 江苏省 南京市 浦口区
联系人:郝经理
联系人电话:15850662640
邮件:381939213@qq.com
网址:http://
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巴洛沙韦,乌帕替尼,索托拉西布,洛普替尼,瑞波替尼,氘可来昔替尼 ,依折麦布,原料药中间体,厂家直供
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参考价格:$460/10mM*1mLinWater
其他供应商价格:
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2021-05-13 瑞来巴坦(Relebactam)
价格:¥需询单

查看所有价格,请点击瑞来巴坦价格