| 常用名 | 阿地溴铵 | CAS号 | 320345-99-1 |
|---|---|---|---|
| 价格 | ¥需询单/1kg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). IC50 value:Target: M3 receptorPreclinically, aclidinium showed potent antagonism of human muscarinic receptors, with a long residence time at M3 receptors and a shorter residence time at M2 receptors, indicating the potential to provide sustained bronchodilation. Aclidinium is rapidly hydrolysed in human plasma, unlike other currently available antimuscarinics including tiotropium. Early clinical studies in healthy subjects have confirmed the low systemic bioavailability and favourable safety profile of single and multiple doses of aclidinium. In a subsequent Phase IIb study, which included 464 patients with moderate to severe COPD, aclidinium displayed long-lasting bronchodilatory activity and was well tolerated. 物理化学性质: CAS号:320345-99-1 常用中文名:阿地溴铵 常用英文名:Aclidinium bromide 分子式:C26H30BrNO4S2 分子量:564.555 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A 储存条件:室温,干燥 |