Lumateperone tosylate
更新时间：2025-09-11 18:13:06
| 常用名 | 甲苯磺酸卢美哌隆 | CAS号 | 1187020-80-9 |
|---|---|---|---|
| 价格 | ￥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a SERT blocker (Ki = 61 nM). IC50 value: 0.54 nM (Ki, for 5-HT2A receptor )Target: 5-HT2A receptorLumateperone also possesses affinity for the D1 receptor (Ki = 52 nM) and weak affinity for the α1A- and α1B-adrenergic receptors (Ki = 173 nM at α1) and D4 receptor. Lumateperone does not significantly bind to the 5-HT2B, 5-HT2C, H1, or mACh receptors. Lumateperone shows a 60-fold difference in its affinities for the 5-HT2A and D2 receptors, which is far greater than that of most or all existing atypical antipsychotics, such as risperidone (12-fold), olanzapine (12.4-fold), and aripiprazole (0.18-fold).[1]in vivo: It is thought that this property may improve the effectiveness and reduce the side effect profile of Lumateperone relative to currently-available antipsychotics, a hypothesis which is supported by the observation of minimal catalepsy in mice treated with Lumateperone.[1] 物理化学性质： CAS号：1187020-80-9 常用中文名：甲苯磺酸卢美哌隆 常用英文名：lumateperone Tosylate 分子式：C31H36FN3O4S 分子量：565.699 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：2-8℃ |
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：lumateperone Tosylate
- 价格： ￥1940.9/25mg ￥582.9/5mg ￥970.9/10mg ￥7184.9/100mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：lumateperoneTosylate
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
- 江西瑞威尔生物科技有限公司
- 江西省 吉安市 峡江县
- 产品名：甲苯磺酸卢美哌隆
- 价格： ￥50000.0/1kg ￥2500.0/20g
- 纯度：98.0%
- 备货期：1天
- 联系人：李经理
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：lumateperone (Tosylate)
- 价格： ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：周经理
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参考价格：$149/10mM*1mLinDMSO