| 常用名 | 螺内酯 | CAS号 | 52-01-7 |
|---|---|---|---|
| 价格 | ¥需询单/1kg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Spironolactone is a potent antagonist of the androgen receptor. Target: Androgen ReceptorSpironolactone is a potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. 5% topical spironolactone cream acts as an antiandrogen in human sebaceous glands, competing with DHT receptors and producing a decrease of labelled DHT. At the concentrations used the effect has been only local. No side-effects were recorded during both studies [1]. Patients who received spironolactone had a significant improvement in the symptoms of heart failure, as assessed on the basis of the New York Heart Association functional class (P 物理化学性质: CAS号:52-01-7 常用中文名:螺内酯 常用英文名:Spironolactone 分子式:C24H32O4S 分子量:416.573 密度:1.2±0.1 g/cm3 沸点:597.0±50.0 °C at 760 mmHg 熔点:207-208 °C(lit.) 闪点:302.3±18.1 °C 储存条件:库房通风低温干燥,与食品原料分开存放 |