丙基硫氧嘧啶
更新时间：2024-05-18 09:08:32
| 常用名 | 丙硫氧嘧啶 | CAS号 | 51-52-5 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 3天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： Propylthiouracil(6-Propyl-2-thiouracil) is a thyroperoxidase and 5'-deiodinase inhibitor. Target: Thyroperoxidase (TPO)Propylthiouracil (PTU) is a thiouracil-derived drug used to treat hyperthyroidism (including Graves' disease) by decreasing the amount of thyroid hormone produced by the thyroid gland [1]. The antithyroid drug 6-propylthiouracil (PTU) was shown to have an unexpectedly prolonged inhibitory effect on iodination in the thyroid glands of rats. Eighteen hours after injection of a relatively small dose, iodination in the thyroid remained inhibited by more than 90% [2]. PTU inhibits the enzyme thyroperoxidase, which normally acts in thyroid hormone synthesis by oxidizing the anion iodide (I-) to iodine (I0), facilitating iodine's addition to tyrosine residues on the hormone precursor thyroglobulin. This is one of the essential steps in the formation of thyroxine (T4). PTU does not inhibit the action of the sodium-dependent iodide transporter located on follicular cells' basolateral membranes. Inhibition of this step requires competitive inhibitors, such as perchlorate and thiocyanate. From Wikipedia. 物理化学性质： CAS号：51-52-5 常用中文名：丙硫氧嘧啶 常用英文名：Propylthiouracil 分子式：C7H10N2OS 分子量：170.232 密度：1.2±0.1 g/cm3 沸点：355.2±34.0 °C at 760 mmHg 熔点：218-220 °C(lit.) 闪点：168.6±25.7 °C 储存条件：Refrigerator |
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：6-正丙基-2-硫代尿嘧啶
- 价格： ￥238.0/100g ￥88.0/25g
- 纯度：98.0%
- 备货期：需询单
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Propylthiouracil
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：6-正丙基-2-硫代尿嘧啶
- 价格： ￥381.9/250mg ￥146.9/1ml ￥254.9/100g ￥107.9/25g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：￥83.3/25g