MCB-613游离态
更新时间：2024-07-15 12:30:21
采购访问：21次
| 常用名 | 4-乙基-2,6-双(吡啶-3-基亚甲基)环己酮 | CAS号 | 1162656-22-5 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： MCB-613 is a potent, pan steroid receptor coactivator (SRC) stimulator.Target: SRCin vitro: MCB-613 exerts the greatest activation of SRC-1 in the primary screen, is confirmed to be a strong activator of all three SRCs. MCB-613 can super-stimulate SRCs' transcriptional activity. MCB-613 increases SRCs' interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS). MCB-613 selectively and reversibly binds to the RID of SRC-3, and selectively kills cancer cells including MCF-7 (breast), PC-3 (prostate), H1299 (lung), and HepG2 (liver) cells, without toxicity to mouse primary hepatocytes and mouse embryonic fibroblasts (MEFs). MCB-613 also increases SRCs' interactions with other coactivators and markedly induces ER stress coupled to the generation of reactive oxygen species (ROS). [1]in vivo: In an MCF-7 breast cancer mouse xenograft model, MCB-613 (20 mg/kg, i.p.) significantly and dramatically inhibits the growth of the tumor while causing no obvious animal toxicity and body weight less. [1] 物理化学性质： CAS号：1162656-22-5 常用中文名：4-乙基-2,6-双(吡啶-3-基亚甲基)环己酮 常用英文名：MCB-613 分子式：C20H20N2O 分子量：304.386 密度：1.159±0.06 g/cm3 沸点：510.4±50.0 °C at 760 mmHg 熔点：N/A 闪点：257.9±36.5 °C 储存条件：-20℃ |
上海念兴实业有限公司
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：MCB-613
- 价格： ￥1699.9/100mg ￥599.9/25mg ￥1049.9/1ml ￥9999.9/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$145/10mM*1mLinDMSO