SR 1903
更新时间：2024-07-15 12:31:57
采购访问：14次
| 常用名 | SR 1903 | CAS号 | 1414248-06-8 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： SR-1903 is a modulator of retinoic acid receptor-related orphan receptor γ (RORγ) and liver X receptor (LXR). It is an inverse agonist of RORγ and an agonist of LXR. It also binds to peroxisome proliferator-activated receptor γ (PPAR) but does not activate it. SR-1903 inhibits LPS-induced expression of triggering receptor expressed on myeloid cells 1 (TREM-1). It also inhibits LPS-induced expression of the LXR target genes IL-6 and IL-33 and increases expression of ABCG1, FASN, and SCD-1. SR-1903 reduces the severity of collagen-induced arthritis. It reduces blood glucose levels in a glucose tolerance test, serum levels of total cholesterol and LDL, body weight, and fat mass in a mouse model of high-fat diet-induced obesity. 物理化学性质： CAS号：1414248-06-8 常用中文名：SR 1903 常用英文名：SR 1903 分子式：C27H27F6N3O 分子量：523.513 密度：1.3±0.1 g/cm3 沸点：559.0±50.0 °C at 760 mmHg 熔点：N/A 闪点：291.9±30.1 °C |
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