| 常用名 | SMN-C2 | CAS号 | 1446311-56-3 |
|---|---|---|---|
| 价格 | 纯度 | 99.01% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: SMN-C2 is a close analogs of RG-7916 act as selective RNA-binding ligands that modulate pre-mRNA splicing; directly binds to the AGGAAG motif on exon 7 of the SMN2 pre-mRNA, and promotes a conformational change in two to three unpaired nucleotides at the junction of intron 6 and exon 7 in both in vitro and in-cell models; increases binding of the splicing modulators, far upstream element binding protein 1 (FUBP1) and its homolog, KH-type splicing regulatory protein (KHSRP), to the SMN-C2/C3-SMN2 pre-mRNA complex and enhances SMN2 splicing. 物理化学性质: CAS号:1446311-56-3 常用中文名:SMN-C2 常用英文名:SMN-C2 分子式:C24H27N5O2 分子量:417.513 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |