| 常用名 | GSK3368715 | CAS号 | 1629013-22-4 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: GSK3368715, aslo known as EPZ019997, is a potent, reversible type I PRMT inhibitor with anti-tumor effects in human cancer models. Inhibition of PRMT5, the predominant type II PRMT, produces synergistic cancer cell growth inhibition when combined with GSK3368715. Interestingly, deletion of the methylthioadenosine phosphorylase gene (MTAP) results in accumulation of the metabolite 2-methylthioadenosine, an endogenous inhibitor of PRMT5, and correlates with sensitivity to GSK3368715 in cell lines. 物理化学性质: CAS号:1629013-22-4 常用中文名:GSK3368715 常用英文名:GSK3368715 分子式:C20H38N4O2 分子量:366.54 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |