| 常用名 | GNE-375 | CAS号 | 1926989-06-1 |
|---|---|---|---|
| 价格 | 纯度 | 99.32% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: GNE-375 is a potent, selective BRD9 inhibitor with IC50 of 5 nM, displays >480-fold selectivity over BRD4, CECR2, and TAF1; decreases BRD9 binding to chromatin, and decreases expression of ALDH1A1, a gene previously shown to be important in drug tolerance; shows remarkable potency in preventing the emergence of a drug tolerant population in EGFR mutant PC9 cells treated with EGFR inhibitors. 物理化学性质: CAS号:1926989-06-1 常用中文名:GNE-375 常用英文名:GNE-375 分子式:C25H29N3O5 分子量:451.523 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |