SUVN-911(compound 9h)
更新时间：2024-07-15 12:34:06
采购访问：15次
| 常用名 | SUVN-911 | CAS号 | 2414674-71-6 |
|---|---|---|---|
| 价格 | 纯度 | 98.0% | |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： SUVN-911 (compound 9h) is a Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.Compound 9h is a potent α4β2 receptor ligand with a Ki value of 1.5 nM. It showed >10 μM binding affinity toward the ganglionic α3β4 receptor apart from showing selectivity over 70 other targets. It is orally bioavailable and showed good brain penetration in rats. Marked antidepressant activity and dose-dependent receptor occupancy in rats support its potential therapeutic utility in the treatment of depression. It does not affect the locomotor activity at doses several folds higher than its efficacy dose. It is devoid of cardiovascular and gastrointestinal side effects. Successful long-term safety studies in animals and phase-1 evaluation in healthy humans for safety, tolerability, and pharmacokinetics paved the way for its further development. 物理化学性质： CAS号：2414674-71-6 常用中文名：SUVN-911 常用英文名：SUVN-911(compound 9h) 分子式：C11H14Cl2N2O 分子量：261.15 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A 储存条件：-20°C，密闭，干燥 |
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- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：SUVN-911
- 价格： ￥5800.9/10mg ￥25500.9/100mg ￥16500.9/50mg ￥3500.9/5mg
- 纯度：99.0%
- 备货期：10天
- 联系人：阿拉丁
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：SUVN-911(compound 9h)
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
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