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RIOK2-IN-1

更新时间:2024-07-17 15:20:19 采购访问:9次

常用名 RIOK2-IN-1 CAS号 1088216-72-1
价格 ¥550.0/100mg ¥850.0/250mg ¥1800.0/1g 纯度 98.0%
备货期 10天 库存 3
 产品详情(用途,包装等)
用途:
RIOK2-IN-1 (com 4) 是有效的选择性 RIOK2 抑制剂 (Kd=150 nM),但细胞活性较低 (IC50=14,600 nM)。而 RIOK2 是一种与多种人类癌症有关的非典型激酶,参与核糖体成熟和细胞周期进展。以 RIOK2-IN-1 为先导化合物的改进得到的小分子抑制剂 CQ211 (HY-147655) 具有良好的体内外活性,抑制 MKN-1 和 HT-29 癌细胞的增殖,并在小鼠异种移植 MKN-1 模型中抑制肿瘤进展。
物理化学性质:
CAS号:1088216-72-1
常用中文名:RIOK2-IN-1
常用英文名:RIOK2-IN-1
分子式:C18H16N2O
分子量:276.33
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A

供应商信息

DC Chemicals Limited 认证供应商

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网址:http://www.dcchemicals.com
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D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.



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