DNL343

更新时间：2024-07-17 15:20:22 采购访问：8次

常用名	DNL343	CAS号	2278265-85-1
价格	￥需询单/100mg ￥需询单/250mg ￥需询单/1g ￥220.0/10ml	纯度	98.0%
备货期	10天	库存	3

产品详情（用途，包装等）用途： DNL343 是具有脑渗透性的激活真核起始因子 2B (eIF2B) 激活剂,可抑制异常整合应激反应 (ISR)。DNL343 可抑制中枢神经系统 (CNS) 的 ISR 活性,逆转神经变性和神经炎症。DNL343 还预防了 eIF2B 功能丧失 (LOF) 突变体突变小鼠的运动功能障碍和过早死亡。DNL343 在由 eIF2B LOF 和慢性 ISR 激活驱动的白质消失病 (VWMD) 研究中具有抑制潜力。物理化学性质： CAS号：2278265-85-1 常用中文名：DNL343 常用英文名：DNL343 分子式：C20H19ClF3N3O4 分子量：457.83 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A

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