DNL343

更新时间：2024-07-17 15:20:22 采购访问：8次

常用名	DNL343	CAS号	2278265-85-1
价格	￥需询单/100mg ￥需询单/250mg ￥需询单/1g ￥220.0/10ml	纯度	98.0%
备货期	10天	库存	3

产品详情（用途，包装等）用途： DNL343 is a brain-penetrating activator of eukaryotic initiation factor 2B (eIF2B) that inhibits the abnormal integrated stress response (ISR). DNL343 inhibits ISR activity in the central nervous system (CNS) and reverses neurodegeneration and neuroinflammation. DNL343 also prevents motor dysfunction and premature death in eIF2B loss-of-function (LOF) mutant mice. DNL343 has inhibitory potential in studies of vanishing white matter disease (VWMD) driven by eIF2B LOF and chronic ISR activation[1]. 物理化学性质： CAS号：2278265-85-1 常用中文名：DNL343 常用英文名：DNL343 分子式：C20H19ClF3N3O4 分子量：457.83 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A

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