(Rac)-CFT7455
更新时间：2024-07-17 16:20:26
采购访问：3次
| 常用名 | CFT7455 | CAS号 | 2504233-68-3 |
|---|---|---|---|
| 价格 | ￥需询单/100mg ￥需询单/250mg ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： CFT7455 is a highly potent and selective degarder of IKZF1/3 with cereblon binding IC50 of 0.4 nM and picomolar DC50.Treatment of the KiJK cell line of anaplastic large cell lymphoma (ALCL) with CFT7455 for 6 hours led to an 89% reduction in IKZF1 protein levels.CFT7455 demonstrated potent antiproliferative activity across a panel of NHL cell lines with MYC, BCL2, and/or BCL6 translocations or rearrangements.CFT7455 is an orally bioavailable.CFT7455 achieved improved in vivo potency and efficacy, including deeper and more durable tumor regressions in models of ALCL, diffuse large B-cell lymphoma (DLBCL) and MCL in xenograft models. 物理化学性质： CAS号：2504233-68-3 常用中文名：CFT7455 常用英文名：CFT7455 分子式：C28H27N3O4 分子量：469.541 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A |
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