| 常用名 | QC-01–175 | CAS号 | 2267290-96-8 |
|---|---|---|---|
| 价格 | ¥需询单/5mg | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: QC-01-175 is a hetero-bifunctional molecule designed to engage both tau and Cereblon (CRBN) to trigger tau ubiquitination and proteasomal degradation (tau PROTAC).QC-01–175 effected clearance of tau in frontotemporal dementia (FTD) patient-derived neuronal cell models, with minimal effect on tau from neurons of healthy controls.QC-01–175 also rescued stress vulnerability in FTD neurons, phenocopying CRISPR-mediated MAPT-knockout. 物理化学性质: CAS号:2267290-96-8 常用中文名:QC-01–175 常用英文名:QC-01–175 分子式:C33H34N6O7 分子量:626.670 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |