MSU38225
更新时间：2024-07-17 16:20:31
采购访问：5次
| 常用名 | MSU38225 | CAS号 | 1629160-83-3 |
|---|---|---|---|
| 价格 | ￥需询单/5mg | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： MSU38225 (MSU-38225) is a novel small molecule that inhibit the Nrf2 pathway, potentially inhibiting Nrf2 transcriptional activity and cancer cell growth;MSU38225 downregulates Nrf2 transcriptional activity and decreases the expression of Nrf2 downstream targets, including NQO1, GCLC, GCLM, AKR1C2, and UGT1A6.MSU38225 strikingly decreases the protein level of Nrf2, which can be blocked by the proteasome inhibitor MG132.Ubiquitination of Nrf2 is enhanced following treatment with MSU38225.By inhibiting production of antioxidants, MSU38225 increases the level of reactive oxygen species (ROS) when cells are stimulated with tert-butyl hydroperoxide (tBHP).MSU38225 also inhibits the growth of human lung cancer cells in both two-dimensional cell culture and soft agar. 物理化学性质： CAS号：1629160-83-3 常用中文名：MSU38225 常用英文名：MSU38225 分子式：C21H19N3 分子量：313.404 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A |
上海念兴实业有限公司
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