| 常用名 | CTCB-405 | CAS号 | 2342614-58-6 |
|---|---|---|---|
| 价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: CTCB-405 (CTCB405) is a small molecule allosteric inhibitor of T. brucei phosphofructokinase (TbPFK) with IC50 of 0.18 uM, ITC Kd of 92 nM, no significant inhibition of human PFKs.CTCB-405 demonstrated in vitro parasite killing potency of the bloodstream form of T. brucei strain Lister 427 (EC50=0.37 uM).CTCB-405 (50, 100 mg/kg) clear parasites in a stage 1 model of HAT infection with 1-day oral dosing and show reduction of parasitaemia in the brain in a pleiomorphic model. 物理化学性质: CAS号:2342614-58-6 常用中文名:CTCB-405 常用英文名:CTCB-405 分子式:C18H19Cl2N3O 分子量:364.27 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |