| 常用名 | NMS-P645 | CAS号 | 1482518-95-5 |
|---|---|---|---|
| 价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/500mg ¥需询单/10ml | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: NMS-P645 is a novel selective inhibitor of pan-Pim kinases with IC50 of 3/73/12 nM for Pim1/2/3, respectively; exhibits excellent selectivity against a large panel of kinases; reverse PIM1-mediated pro-survival signals in prostate cells, such as activation of STAT3 through Tyr705 phosphorylation and resistance to taxane-based treatments; induces a significant anti-proliferative response in PCa cells combined with GDC-0941. 物理化学性质: CAS号:1482518-95-5 常用中文名:NMS-P645 常用英文名:NMS-P645 分子式:C28H38ClN5O2 分子量:512.095 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |