| 常用名 | Dynein2-IN-37 | CAS号 | 1823133-56-7 |
|---|---|---|---|
| 价格 | ¥需询单/100mg ¥需询单/250mg ¥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Dynein2-IN-37 (Ciliobrevin analog 37) is a potent, selective cytoplasmic dynein 2 ATPase activity antagonist with IC50 of 11 uM, shows weak inhibition for dynein 2 (IC50=280 uM); directly targets the heavy chains of both dynein isoforms and explore the structure-activity landscape of these inhibitors in vitro and in cells; inhibits retrograde ciliary GLI2 transport more strongly than ciliobrevin A, effectively disrupts Hedgehog signaling, intraflagellar transport, and ciliogenesis. 物理化学性质: CAS号:1823133-56-7 常用中文名:Dynein2-IN-37 常用英文名:Dynein2-IN-37 分子式:C25H17Cl2N3O3 分子量:478.329 密度:N/A 沸点:N/A 熔点:N/A 闪点:N/A |