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Dynein2-IN-37

更新时间:2026-01-13 13:01:36 采购访问:6次

常用名 Dynein2-IN-37 CAS号 1823133-56-7
价格 ¥需询单/100mg ¥需询单/250mg ¥需询单/1g 纯度 98.0%
备货期 10天 库存 现货
 产品详情(用途,包装等)
用途:
Dynein2-IN-37 (Ciliobrevin analog 37) is a potent, selective cytoplasmic dynein 2 ATPase activity antagonist with IC50 of 11 uM, shows weak inhibition for dynein 2 (IC50=280 uM); directly targets the heavy chains of both dynein isoforms and explore the structure-activity landscape of these inhibitors in vitro and in cells; inhibits retrograde ciliary GLI2 transport more strongly than ciliobrevin A, effectively disrupts Hedgehog signaling, intraflagellar transport, and ciliogenesis.
物理化学性质:
CAS号:1823133-56-7
常用中文名:Dynein2-IN-37
常用英文名:Dynein2-IN-37
分子式:C25H17Cl2N3O3
分子量:478.329
密度:N/A
沸点:N/A
熔点:N/A
闪点:N/A

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