AKR1C3 inhibitor KV-37
更新时间：2024-07-17 16:21:02
采购访问：13次
| 常用名 | AKR1C3 inhibitor KV-37 | CAS号 | 1954693-22-1 |
|---|---|---|---|
| 价格 | ￥需询单/100mg ￥需询单/250mg ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 10天 | 库存 | 现货 |
| 产品详情（用途，包装等）
用途： AKR1C3 inhibitor KV-37 is a potent, isoform selective and metabolically stable inhibitor of Aldo-keto reductase 1C3 (AKR1C3) with IC50 of 66 nM, displays 109-fold selectivity over AKR1C2; shows competitive enzyme inhibition versus AKR1C3 with Ki of 3 uM E.NADPH; inhibits AKR1C3 activity in prostate cancer cell lines by inhibiting the conversion of Δ4-AD to testosterone, exhibits greater reduction of prostate cancer cell viability compared to baccharin; sensitizes CRPC cell lines (22Rv1 and LNCaP1C3) towards the anti-tumor effects of enzalutamide, also reduces androgen receptor (AR) transactivation and prostate specific antigen (PSA) expression levels in CRPC cells lines; reduces cancer cell growth in vivo in 22Rv1 xenograft models. 物理化学性质： CAS号：1954693-22-1 常用中文名：AKR1C3 inhibitor KV-37 常用英文名：AKR1C3 inhibitor KV-37 分子式：C23H25NO3 分子量：363.457 密度：N/A 沸点：N/A 熔点：N/A 闪点：N/A |
上海念兴实业有限公司
认证状态：已认证供应商
商品数：403768件
电话：18916513247
地址：2222 Huancheng Road, Juyuan New District, Jiading District, Shanghai
地区： 上海市 上海市 普陀区
联系人：小陈
联系人电话：0086-021-52280163
邮件：sales@echemcloud.com
网址：http://www.echemcloud.com
主要市场：
年贸易额：
外贸占销售比例：
主要合作伙伴：