| 常用名 | 吡喹酮 | CAS号 | 55268-74-1 |
|---|---|---|---|
| 价格 | ¥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Praziquantel is an anthelmintic effective against flatworms.Target: AntiparasiticPraziquantel is the drug of choice for treatment of all human schistosomes. Infected mice were treated with increasing Praziquantel doses until the highest dose of 3 × 300 mg/Kg was reached. The effect of Praziquantel treatment on the parasite population was assessed using five polymorphic microsatellite markers. Parasitological and genetic data were compared with those of the untreated control. After six parasite generations submitted to treatment, it was possible to obtain a S. mansoni population with decreased susceptibility to Praziquantel. In our experiments we also observed that female worms were more susceptible to Praziquantel than male worms [1, 2]. 作用: 本品主要通过5-HT样作用使宿主体内血吸虫、绦虫产生痉挛性麻痹脱落,对多数绦虫成虫和未成熟虫体都有较好效果,同时能影响虫体肌细胞内钙离子通透性,使钙离子内流增加,抑制肌浆网钙泵的再摄取,虫体肌细胞内钙离子含量大增,使虫体麻痹脱落。 物理化学性质: CAS号:55268-74-1 常用中文名:吡喹酮 常用英文名:Praziquantel 分子式:C19H24N2O2 分子量:312.406 密度:1.2±0.1 g/cm3 沸点:544.1±50.0 °C at 760 mmHg 熔点:136-142ºC 闪点:254.6±22.5 °C 储存条件:通风低温干燥 |