| 常用名 | 硝唑尼特 | CAS号 | 55981-09-4 |
|---|---|---|---|
| 价格 | ¥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Nitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. (IC50 for canine influenza virus ranges from 0.17 to 0.21 μM).Target: OthersNitazoxanide is a synthetic nitrothiazolyl-salicylamide derivative and an antiprotozoal agent. In vitro studies demonstrated much broader activity. Dr. Rossignol co-founded Romark Laboratories, with the goal of bringing nitazoxanide to market as an anti-parasitic drug. Initial studies in the USA were conducted in collaboration with Unimed Pharmaceuticals, Inc. (Marietta, GA) and focused on development of the drug for treatment of cryptosporidiosis in AIDS.The anti-protozoal activity of nitazoxanide is believed to be due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme dependent electron transfer reaction which is essential to anaerobic energy metabolism. It has also been shown to have activity against influenza A virus in vitro. The mechanism appears to be by selectively blocking the maturation of the viral hemagglutinin at a stage preceding resistance to endoglycosidase H digestion. This impairs hemagglutinin intracellular trafficking and insertion of the protein into the host plasma membrane. 物理化学性质: CAS号:55981-09-4 常用中文名:硝唑尼特 常用英文名:Nitazoxanide 分子式:C12H9N3O5S 分子量:307.282 密度:1.5±0.1 g/cm3 沸点:N/A 熔点:202ºC 闪点:N/A 储存条件:-20°C Freezer |