| 常用名 | 新生霉素(钠盐) | CAS号 | 1476-53-5 |
|---|---|---|---|
| 价格 | ¥200.0/250mg ¥350.0/1g ¥1500.0/5g | 纯度 | 90.0% |
| 备货期 | 2天 | 库存 | 1 g |
| 产品详情(用途,包装等)
用途: Novobiocin Sodium is an antibiotic compound derived from Streptomyces niveus.Target: AntibacterialNovobiocin, also known as albamycin or cathomycin, is an aminocoumarin antibiotic that is produced by the actinomycete Streptomyces niveus, which has recently been identified as a subjective synonym for S. spheroides a member of the order Actinobacteria . Other aminocoumarin antibiotics include clorobiocin and coumermycin A1. The molecular basis of action of novobiocin, and other related drugs clorobiocin and coumermycin A1 has been examined. Aminocoumarins are very potent inhibitors of bacterial DNA gyrase and work by targeting the GyrB subunit of the enzyme involved in energy transduction. Novobiocin as well as the other aminocoumarin antibiotics act as competitive inhibitors of the ATPase reaction catalysed by GyrB. The potency of novobiocin is considerably higher than that of the fluoroquinolones that also target DNA gyrase, but at a different site on the enzyme. The GyrA subunit is involved in the DNA nicking and ligation activity [1-4]. 物理化学性质: CAS号:1476-53-5 常用中文名:新生霉素(钠盐) 常用英文名:Novobiocin Sodium Salt 分子式:C31H35N2NaO11 分子量:634.60600 密度:1.42g/cm3 沸点:848.2ºC at 760mmHg 熔点:215-220ºC 闪点:466.8ºC 储存条件:-20°C |