| 常用名 | 克霉唑 | CAS号 | 23593-75-1 |
|---|---|---|---|
| 价格 | ¥300.0/1g ¥600.0/5g | 纯度 | 98.0% |
| 备货期 | 2天 | 库存 | 5 kg |
| 产品详情(用途,包装等)
用途: Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.Target: Antifungal; CYPClotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete's foot and jock itch.It is commonly available as an over-the-counter substance in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often applied in liquid form, as ear drops.The antimycotic drug clotrimazole inhibits the function of the gastric H,K-ATPase in a manner similar to that observed for the Na,K-ATPase. Because of the high hydrophobicity of the compound, the interaction between clotrimazole and the ion pump occurs at the membrane domain in the apolar core of the membrane. The enzymatic activity was inhibited with a half-saturating concentration of 5.2 microM. Various partial reactions of the pump cycle were analyzed with the electrochromic styryl dye RH421 that has been widely used to study the transport mechanism of P-type ATPases. 物理化学性质: CAS号:23593-75-1 常用中文名:克霉唑 常用英文名:Clotrimazole 分子式:C22H17ClN2 分子量:344.837 密度:1.1±0.1 g/cm3 沸点:482.3±40.0 °C at 760 mmHg 熔点:147-149ºC 闪点:245.5±27.3 °C 储存条件:Store at RT. |