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Lineage Tracing across 10 Years

10.1016/j.stem.2017.05.017

2017-06-01

Think back to where you were and what you were doing 10 years ago. Maybe you were in graduate school, maybe even high school, or perhaps you had just started your first lab and were working out how to transition from being a postdoc to being a leader of a sci...

Opportunities in Reprogramming: Fred Gage, Kristin Baldwin, and Hongkui Deng

10.1016/j.stem.2017.05.016

2017-06-01

In an interview withCell Stem Cellfor our tenth anniversary, Drs. Fred Gage, Kristin Baldwin, and Hongkui Deng discuss exciting breakthroughs and remaining challenges in the fields of iPSC reprogramming, direct reprogramming, and in vivo reprogramming.

Looking Back: Single-Cell Analysis

10.1016/j.stem.2017.05.015

2017-06-01

Over the past few years, burgeoning single-cell analyses platforms have unlocked access to previously unobtainable biological information about stem cell populations. For our tenth anniversary, we asked authors that cited a selection of our most popular paper...

Advances in Organoid Technology: Hans Clevers, Madeline Lancaster, and Takanori Takebe

10.1016/j.stem.2017.05.014

2017-06-01

In an interview withCell Stem Cellfor our tenth anniversary, Drs. Hans Clevers, Madeline Lancaster, and Takanori Takebe discuss the most exciting organoid applications, remaining hurdles to more widespread technology adoption, and promising opportunities.

From Cell Stem Cell to Clinical Trials: The Biotech Journey of Two Papers

10.1016/j.stem.2017.05.013

2017-06-01

How many of the authors who publish in Cell Stem Cell dream that their work will eventually wind up in the clinic? Probably quite a few. In the 10 years since its launch, Cell Stem Cell has featured many innovative discoveries, and several of them have gone o...

The Future of Genome Editing: Kiran Musunuru, Danwei Huangfu, and Stanley Qi

10.1016/j.stem.2017.05.012

2017-06-01

In an interview withCell Stem Cellfor our tenth anniversary, Drs. Kiran Musunuru, Danwei Huangfu, and Stanley Qi discuss the rapid technological advancements and their scientific, societal, and industrial implications.

Looking Back: Epigenomics

10.1016/j.stem.2017.05.011

2017-06-01

Our understanding of how changes in epigenomics facilitate reprogramming and lineage specification has grown extensively over the last decade. For our tenth anniversary, we asked authors who cited a selection of our most popular papers in this area about how ...

Racing to Uncover the Link between Zika Virus and Microcephaly

10.1016/j.stem.2017.05.010

2017-06-01

In this Backstory, we give a behind-the-scenes account of the collaboration leading to our 2016 paper on Zika virus (ZIKV) infection of neural progenitor cells (http://www.cell.com/cell-stem-cell/fulltext/S1934-5909(16)00106-5). It was one of the first clues ...

Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions

10.1016/j.stem.2017.05.009

2017-06-01

(Cell Stem Cell 20, 858–873; June 1, 2017)

Adipocytes at the Core of Bone Function

10.1016/j.stem.2017.05.008

2017-06-01

Marrow adipose tissue (MAT) is a specialized adipose tissue with endocrine function found in bone marrow. In this issue ofCell Stem Cell, Ambrosi et al. (2017) identify a stem cell population in the bone marrow that can give rise to both osteogenic and adipog...