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Looking Back: Aging and Regeneration

10.1016/j.stem.2017.05.007

2017-06-01

Developing our understanding of how stem cell decline contributes to aging and its associated diseases promotes promising approaches to enhance stem cell regenerative capacity. For our tenth anniversary, we asked authors who cited a selection of our most popu...

Looking Back: Disease Modeling

10.1016/j.stem.2017.05.006

2017-06-01

Over the past decade, the growth of stem cell-based models of human disorders has contributed to novel drug discovery and precision medicine possibilities. For our tenth anniversary, we asked authors who cited a selection of our most popular papers in this ar...

Looking Back: Cancer Stem Cells

10.1016/j.stem.2017.05.005

2017-06-01

Over the past decade, our growing understanding of cancer stem cell characteristics and function continues to guide innovative new treatments to eradicate cancer. For our tenth anniversary, we asked authors who cited a selection of our most popular papers in ...

Surface Markers Guide the Journey toward Naive Pluripotency

10.1016/j.stem.2017.05.004

2017-06-01

Several protocols have managed to reset human primed PSCs to the naive state. In this issue ofCell Stem Cell, Collier et al. (2017) report a set of surface markers that identify which cells are susceptible to resetting and suggest a potential roadmap for the ...

Gli-fully Halting the Progression of Fibrosis

10.1016/j.stem.2017.05.003

2017-06-01

Activating triggers, selective markers, and the residual regenerative potential of scar-forming myofibroblasts are largely determined by their origin. In this issue ofCell Stem Cell, Schneider et al. report that bone marrow myofibroblasts derive from Gli1+mes...

Mitotic Bookmarking: Maintaining the Stem Cell Identity during Mitosis

10.1016/j.stem.2017.05.002

2017-06-01

InCell Reports, Liu et al. (2017) investigate mechanisms for how pluripotent stem cells maintain their identity during cell division. They show that the histone mark H3K27ac and pluripotency transcription factors remain associated with mitotic chromatin in ES...

Mitotic Bookmarking: Maintaining the Stem Cell Identity during Mitosis

10.1016/j.stem.2017.05.002

2017-06-01

In Cell Reports, Liu et al. (2017) investigate mechanisms for how pluripotent stem cells maintain their identity during cell division. They show that the histone mark H3K27ac and pluripotency transcription factors remain associated with mitotic chromatin in E...

Gli-fully Halting the Progression of Fibrosis

10.1016/j.stem.2017.05.003

2017-06-01

Activating triggers, selective markers, and the residual regenerative potential of scar-forming myofibroblasts are largely determined by their origin. In this issue of Cell Stem Cell, Schneider et al. report that bone marrow myofibroblasts derive from Gli1+ m...

Surface Markers Guide the Journey toward Naive Pluripotency

10.1016/j.stem.2017.05.004

2017-06-01

Several protocols have managed to reset human primed PSCs to the naive state. In this issue of Cell Stem Cell, Collier et al. (2017) report a set of surface markers that identify which cells are susceptible to resetting and suggest a potential roadmap for the...

Looking Back: Cancer Stem Cells

10.1016/j.stem.2017.05.005

2017-06-01

Over the past decade, our growing understanding of cancer stem cell characteristics and function continues to guide innovative new treatments to eradicate cancer. For our tenth anniversary, we asked authors who cited a selection of our most popular papers in ...