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The Effect of Lean‐Seafood and Non‐Seafood Diets on Fecal Metabolites and Gut Microbiome: Results from a Randomized Crossover Intervention Study

10.1002/mnfr.201700976

2018-04-16

The impact of dietary protein types on the gut microbiome is scarcely studied. The aim of the present study is therefore to examine the effects of lean‐seafood and non‐seafood proteins on the gut microbiome composition and activity and elucidate potential ass...

Bioavailability of Isothiocyanates From Broccoli Sprouts in Protein, Lipid, and Fiber Gels

10.1002/mnfr.201700837

2018-04-14

Optimization of bioavailability of dietary bioactive health‐beneficial compounds is as important as increasing their concentration in foods. The aim of this study is to explore the change in bioavailability of isothiocyanates (ITCs) in broccoli sprouts incorp...

Flaxseed Oil Attenuates Intestinal Damage and Inflammation by Regulating Necroptosis and TLR4/NOD Signaling Pathways Following Lipopolysaccharide Challenge in a Piglet Model

10.1002/mnfr.201700814

2018-04-14

Flaxseed oil is a rich source of α‐linolenic acid (ALA), which is the precursor of the long‐chain n‐3 polyunsaturated fatty acids (PUFAs), including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). This study investigates the protective effect of f...

Sugary Kefir Strain Lactobacillus mali APS1 Ameliorated Hepatic Steatosis by Regulation of SIRT‐1/Nrf‐2 and Gut Microbiota in Rats

10.1002/mnfr.201700903

2018-04-03

Non‐alcoholic fatty liver disease (NAFLD) is a common disease that is concomitant with obesity, resulting in increased mortality. To date, the efficiency of NAFLD treatment still needs to be improved. Therefore, we aimed to evaluate the effect of Lactobacillu...

Changes in Plasma Metabolite Concentrations after a Low‐Glycemic Index Diet Intervention

10.1002/mnfr.201700975

2018-03-30

: To examine whether a low‐glycemic index (LGI) diet improves a set of plasma metabolites related to different metabolic diseases and compared to a high‐glycemic index (HGI) diet and a low‐fat (LF) diet.

Metabolic Regulation of Methionine Restriction in Diabetes

10.1002/mnfr.201700951

2018-03-30

Although the effects of dietary methionine restriction have been investigated in the physiology of aging and diseases related to oxidative stress, the relationship between methionine restriction and the development of metabolic disorders has not been explored...

Phycoerythrin‐Derived Tryptic Peptide of a Red Alga Pyropia yezoensis Attenuates Glutamate‐Induced ER Stress and Neuronal Senescence in Primary Rat Hippocampal Neurons

10.1002/mnfr.201700469

2018-03-30

Glutamate excitotoxicity has been observed in association with neurodegenerative disorders. This study aimed to investigate whether a phycoerythrin‐derived tryptic peptide of Pyropia yezoensis (PYP) reduces glutamate‐induced excitotoxicity and neuronal senesc...

Constituents of Mediterranean Spices Counteracting Vascular Smooth Muscle Cell Proliferation: Identification and Characterization of Rosmarinic Acid Methyl Ester as a Novel Inhibitor

10.1002/mnfr.201700860

2018-03-30

Aberrant vascular smooth muscle cell (VSMC) proliferation is involved in atherosclerotic plaque formation and restenosis. Mediterranean spices have been reported to confer cardioprotection, but their direct influence on VSMCs has largely not been investigated...

Urinary Metabolomics Profiles Associated to Bovine Meat Ingestion in Humans

10.1002/mnfr.201700834

2018-03-27

The impact of meat consumption on human health is widely examined in nutritional epidemiological studies, especially due to the connection between the consumption of red and processed meat and the risk of colon cancer. Food questionnaires do not assess the ex...

Hepatic Lipogenesis and Brain Fatty Acid Profile in Response to Different Dietary n6/n3 Ratios and DHA/EPA Supplementation in Streptozotocin Treated Rats

10.1002/mnfr.201701007

2018-03-26

: We investigated the interaction between streptozotocin‐induced diabetes and dietary n6/n3 ratio, and its influence on lipogenesis.