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Impact of evolving greenhouse gas forcing on the warming signal in regional climate model experiments
10.1038/s41467-018-03527-y 2018-04-03 Variations in the atmospheric concentrations of greenhouse gases (GHG) may not be included as external forcing when running regional climate models (RCMs); at least, this is a non-regulated, non-documented practice. Here we investigate the so far unexplored i... |
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Small molecules promote CRISPR-Cpf1-mediated genome editing in human pluripotent stem cells
10.1038/s41467-018-03760-5 2018-04-03 Human pluripotent stem cells (hPSCs) have potential applications in biological studies and regenerative medicine. However, precise genome editing in hPSCs remains time-consuming and labor-intensive. Here we demonstrate that the recently identified CRISPR-Cpf1... |
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Biosynthesis of fragin is controlled by a novel quorum sensing signal
10.1038/s41467-018-03690-2 2018-03-30 Members of the diazeniumdiolate class of natural compounds show potential for drug development because of their antifungal, antibacterial, antiviral, and antitumor activities. Yet, their biosynthesis has remained elusive to date. Here, we identify a gene clus... |
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Author Correction: Menin enhances c-Myc-mediated transcription to promote cancer progression
10.1038/ncomms16195 2018-03-30 Author Correction: Menin enhances c-Myc-mediated transcription to promote cancer progression |
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Biomimetic temporal self-assembly via fuel-driven controlled supramolecular polymerization
10.1038/s41467-018-03542-z 2018-03-30 Temporal control of supramolecular assemblies to modulate the structural and transient characteristics of synthetic nanostructures is an active field of research within supramolecular chemistry. Molecular designs to attain temporal control have often taken in... |
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Publisher Correction: Hysteresis of ligand binding in CNGA2 ion channels
10.1038/ncomms16207 2018-03-30 Publisher Correction: Hysteresis of ligand binding in CNGA2 ion channels |
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Publisher Correction: Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC
10.1038/ncomms16196 2018-03-30 Publisher Correction: Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC |
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Author Correction: Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis
10.1038/ncomms16211 2018-03-30 Author Correction: Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis |
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Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries
10.1038/ncomms16203 2018-03-30 Author Correction: The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries |
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RodZ modulates geometric localization of the bacterial actin MreB to regulate cell shape
10.1038/s41467-018-03633-x 2018-03-29 In the rod-shaped bacterium Escherichia coli, the actin-like protein MreB localizes in a curvature-dependent manner and spatially coordinates cell-wall insertion to maintain cell shape, although the molecular mechanism by which cell width is regulated remains... |