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Improving treatment outcome assessment in a mouse tuberculosis model
10.1038/s41598-018-24067-x 2018-04-09 Preclinical treatment outcome evaluation of tuberculosis (TB) occurs primarily in mice. Current designs compare relapse rates of different regimens at selected time points, but lack information about the correlation between treatment length and treatment outc... |
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Coarse particulate matter (PM2.5–10) in Los Angeles Basin air induces expression of inflammation and cancer biomarkers in rat brains
10.1038/s41598-018-23885-3 2018-04-09 Air pollution is linked to brain inflammation, which accelerates tumorigenesis and neurodegeneration. The molecular mechanisms that connect air pollution with brain pathology are largely unknown but seem to depend on the chemical composition of airborne parti... |
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Ion Permeation Mechanism in Epithelial Calcium Channel TRVP6
10.1038/s41598-018-23972-5 2018-04-09 Calcium is the most abundant metal in the human body that plays vital roles as a cellular electrolyte as well as the smallest and most frequently used signaling molecule. Calcium uptake in epithelial tissues is mediated by tetrameric calcium-selective transie... |
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The Scientific Basis and Advantage of Human Experiential Assessment in the quality control of Chinese Herbal Medicines exampling as Schisandrae Chinensis Fructus
10.1038/s41598-018-23619-5 2018-04-09 Experiential quality assessment(EQA) is an important sensory analysis for judging herbal quality grades. Because of the high empirical utility of expert experience, the consistency, science and inheritance of such experience are continuously in dispute. To ex... |
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The focal alteration and causal connectivity in children with new-onset benign epilepsy with centrotemporal spikes
10.1038/s41598-018-23336-z 2018-04-09 The aim of the current study was to find the epileptic focus and examine its causal relationship to other brain regions in children with new-onset benign childhood epilepsy with centrotemporal spikes (BECTS). Resting-state functional magnetic resonance imagin... |
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Temporal and spatial changes of macrobenthos community in the regions frequently occurring black water aggregation in Lake Taihu
10.1038/s41598-018-24058-y 2018-04-09 Seasonal survey was performed from August 2015 to May 2016 at 50 sampling sites in Lake Taihu to determine the spatial and temporal changes in macrobenthos community and their relationships with environmental variables. A total of 58 macrobenthos species were... |
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Formation of trihalomethanes as disinfection byproducts in herbal spa pools
10.1038/s41598-018-23975-2 2018-04-09 Herbal spa treatments are favorite recreational activities throughout the world. The water in spas is often disinfected to control pathogenic microorganisms and guarantee hygiene. However, chlorinated water may cause the formation of disinfection byproducts (... |
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Fine Needle-Diathermy Regresses Pathological Corneal (Lymph)Angiogenesis and Promotes High-Risk Corneal Transplant Survival
10.1038/s41598-018-24037-3 2018-04-09 Pathological corneal hem- and lymphangiogenesis are prime risk factors for corneal graft rejection. Fine needle-diathermy (FND) is an option to regress corneal blood vessels; however, whether this treatment besides clinically visible blood vessels also affect... |
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All-Optical Reinforcement Learning In Solitonic X-Junctions
10.1038/s41598-018-24084-w 2018-04-09 Ethology has shown that animal groups or colonies can perform complex calculation distributing simple decision-making processes to the group members. For example ant colonies can optimize the trajectories towards the food by performing both a reinforcement (o... |
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A transmission electron microscope study of Néel skyrmion magnetic textures in multilayer thin film systems with large interfacial chiral interaction
10.1038/s41598-018-23799-0 2018-04-09 Skyrmions in ultrathin ferromagnetic metal (FM)/heavy metal (HM) multilayer systems produced by conventional sputtering methods have recently generated huge interest due to their applications in the field of spintronics. The sandwich structure with two correc... |