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Self-assembly two-dimensional gold nanoparticles film for sensitive analysis nontargeted of food additives with Surface-enhanced Raman spectroscopy
10.1039/C8AN00540K 2018-04-11 The emergence of different food additives and their active metabolites have been found to cause serious problems to human health. Thus, considering the potential effects on human health, developing the sensitive and credible analytical method in different foo... |
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In-vitro and ex-vivo measurements of biophysical properties of blood by using microfluidic platforms and animal models
10.1039/C8AN00231B 2018-04-11 Haemorheologically impaired microcirculation, such as blood clotting or abnormal blood flow, causes interrupted blood flows in vascular networks. The biophysical properties of blood, including blood viscosity, blood viscoelasticity, haematocrit, red blood bel... |
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Dependence of cell adhesion on extracellular matrix materials formed on pore bridge boundaries by nanopore opening and closing geometry
10.1039/C8AN00429C 2018-04-11 In this study, we report experimental results for characterization of the growth and formation of pore bridge materials that modified the adhesion structures of cells cultured on nanomembranes with opening and closing geometry. To perform the proof-of-concept... |
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One-step isothermal detection of multiple KRAS mutations by forming SNP specific hairpins on a gold nanoshell
10.1039/C8AN00525G 2018-04-11 We developed a one-step isothermal method for typing mutiple KRAS mutations using designed set of primers to form a hairpin on a gold nanoshell upon being ligated by a SNP specific DNA ligase after binding of targets. As a result, we could detect as low as 20... |
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Simple preparation and highly selective detection of silver ions using an electrochemical sensor based on sulfur-doped graphene and a 3,3′,5,5′-tetramethylbenzidine composite modified electrode
10.1039/C7AN02084H 2018-04-10 A novel electrochemical sensor based on sulfur (S)-doped graphene (S-Gr) and a 3,3′,5,5′-tetramethylbenzidine (TMB) composite (S-Gr-TMB) modified glassy carbon (GCE) electrode for highly selective quantitative detection of silver ions (Ag+) were fabricated. T... |
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A Facile Graphene Oxide-Based Fluorescent Nanosensor for in Situ “Turn-on” Detection of Telomerase Activity
10.1039/C8AN00402A 2018-04-10 A facile and sensitive method for the quantitative detection of telomerase and in situ imaging of intracellular telomerase is developed by using a graphene oxide (GO)-based fluorescent nanosensor. The nanosensor consists of a fluorescent DNA (P1) adsorbed on ... |
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PEGylated Nanographene–mediated Metallic Nanoparticle Clusters for Surface Enhanced Raman Scattering–based Biosensing
10.1039/C8AN00329G 2018-04-10 Surface-enhanced Raman scattering (SERS) is an optical spectroscopy technique that can detect a variety of analytes with high sensitivity and selectivity without any labels. Controlled clustering of metallic nanoparticles to prepare a new class of SERS nanota... |
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A photoluminescence “switch-on” nanosensor composed of nitrogen and sulphur co-doped carbon dots and gold nanoparticles for discriminative detection of glutathione
10.1039/C8AN00168E 2018-04-10 Biological thiols play a key role in biological processes and are involved in a variety of diseases. The discriminative detection of biological thiols is still challenging. In this contribution, a platform, an energy transfer-based quenching system composed o... |
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In vitro antibacterial activity of oxide and non-oxide bioceramics for arthroplastic devices: II. Fourier transform infrared spectroscopy
10.1039/C8AN00234G 2018-04-10 The metabolic response of Gram-positive Staphylococcus epidermidis (S. epidermidis) bacteria to bioceramic substrates was probed by means of Fourier transform infrared spectroscopy (FTIR). Oxide zirconia-toughened alumina (ZTA) and non-oxide silicon nitride (... |
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Mechanism and regularity for quenching effect of bases on fluorophore: The base-quenched probe method
10.1039/C8AN00116B 2018-04-09 The base-quenched probe method for detecting Single nucleotide polymorphisms (SNPs) relies on real-time PCR and melting-curve analysis, which might require only one pair of primers and one probe. At present, it has been successfully applied to detect SNPs of ... |