N,N-二乙基乙二胺

N,N-二乙基乙二胺用途

【用途一】
在医药上用于合成盐酸普鲁卡因胺、盐酸氯普鲁卡因、辛可卡因、盐酸硫必利
【用途二】
N,N-二乙基乙二胺用作精细化学品的中间体，可生产抗心律失常药普鲁卡因胺、局部麻醉药盐酸地布卡因及酶抑宁等。也用来生产助剂产品，例如，用于制取色必明BCH（Sapamine BCH）。

N,N-二乙基乙二胺名称

[ CAS 号 ]:
100-36-7

[ 中文名 ]:
N,N-二乙基乙二胺

[ 英文名 ]:
2-aminoethyldiethylamine

[中文别名 ]:

[英文别名 ]:

N-[2-(Diethylamino)ethyl]amine
2-aminoethyldiethylamine
2-Diethylaminoethylamine
N,N-Diethyl-1,2-ethanediamine
N1,N1-Diethylethane-1,2-diamine
N',N'-diethylethane-1,2-diamine
N,N-Diethylethane-1,2-diamine
EINECS 202-844-7
MFCD00008176
1,2-Ethanediamine, N,N-diethyl-

N,N-二乙基乙二胺物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
142.5±8.0 °C at 760 mmHg

[ 熔点 ]:
<-70ºC

[ 分子式 ]:
C₆H₁₆N₂

[ 分子量 ]:
116.205

[ 闪点 ]:
30.6±0.0 °C

[ 精确质量 ]:
116.131348

[ PSA ]:
29.26000

[ LogP ]:
0.21

[ 外观性状 ]:
无色液体

[ 蒸汽压 ]:
5.6±0.3 mmHg at 25°C

[ 折射率 ]:
1.448

[ 储存条件 ]:
包装完整、轻装轻卸,库房通风、远离明火、高温、与氧化剂、酸分开存放

[ 水溶解性 ]:
MISCIBLE

N,N-二乙基乙二胺MSDS

N,N-二乙基乙二胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KV3500000

CHEMICAL NAME :: Ethylenediamine, N,N-diethyl-

CAS REGISTRY NUMBER :: 100-36-7

BEILSTEIN REFERENCE NO. :: 0605299

LAST UPDATED :: 199806

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H16-N2

MOLECULAR WEIGHT :: 116.24

WISWESSER LINE NOTATION :: Z2N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2830 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 820 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954

N,N-二乙基乙二胺安全信息

[ 符号 ]:

GHS02, GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H311-H314-H332

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R10;R21;R35

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45-S25-S16

[ 危险品运输编码 ]:
UN 2685 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
KV3500000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
29212900

N,N-二乙基乙二胺合成路线

N,N-二乙基乙二胺上下游产品

N,N-二乙基乙二胺上游产品

N,N-二乙基乙二胺下游产品

N,N-二乙基乙二胺制备

由丙烯腈经水解、加成、降解而得；另一种生产方法是由乙二氨基乙腈加氢制得该品。

N,N-二乙基乙二胺海关

[ 海关编码 ]: 2921290000

[ 中文概述 ]:
2921290000. 其他无环多胺及其衍生物及它们的盐. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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