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D-松醇

D-松醇用途

D-pinitol (3-O-Methyl-D-chiro-inositol) 是一种天然化合物,存在于几种植物中,如松科和豆科植物。D-pinitol 具有降血糖活性和心血管系统保护作用。

D-松醇名称

[ CAS 号 ]:
10284-63-6

[ 中文名 ]:
D-松醇

[ 英文名 ]:
D-Pinitol

[英文别名 ]:

PINITOL,D
Matezitol
MFCD00216659
D-PINTIOL
CathartoMannitol
3-O-methyl ether of D-chiro-inositol
3-O-Methyl-D-chiro-inositol
1D-3-O-methyl-chiro-inositol
Sennitol
O-methyl inositol

D-松醇生物活性

[ 描述 ]:

D-pinitol (3-O-Methyl-D-chiro-inositol) 是一种天然化合物,存在于几种植物中,如松科和豆科植物。D-pinitol 具有降血糖活性和心血管系统保护作用。

[ 相关类别 ]:

研究领域 >> 心血管疾病

信号通路 >> 其他 >> 其他

[体外研究]

D-品醇通过诱导p53和bax以及抑制bcl-2和nf-κb[3]促进MCF-7细胞凋亡。

[参考文献]

[1]. Gao Y, et al. Effects of D-Pinitol on Insulin Resistance through the PI3K/Akt Signaling Pathway in Type 2Diabetes Mellitus Rats. J Agric Food Chem. 2015 Jul 8;63(26):6019-26.

[2]. Moreira LN, et al. Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in MouseMesenteric Artery. Front Pharmacol. 2018 May 22;9:528.

[3]. Rengarajan T, et al. D-pinitol promotes apoptosis in MCF-7 cells via induction of p53 and Bax and inhibition of Bcl-2 and NF-κB. Asian Pac J Cancer Prev. 2014;15(4):1757-62.

D-松醇物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
317.2±42.0 °C at 760 mmHg

[ 熔点 ]:
178-185ºC

[ 分子式 ]:
C₇H₁₄O₆

[ 分子量 ]:
194.182

[ 闪点 ]:
145.6±27.9 °C

[ 精确质量 ]:
194.079041

[ PSA ]:
110.38000

[ LogP ]:
-0.74

[ 外观性状 ]:
白色至灰白色晶体

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.588

[ 储存条件 ]:
室温，密封，干燥

[ 水溶解性 ]:
水溶性：可溶

D-松醇MSDS

D-松醇安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
C;F

[ 风险声明 (欧洲) ]:
R11

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2909499000

D-松醇合成路线

D-松醇上下游产品

D-松醇上游产品

D-松醇下游产品

D-松醇海关

[ 海关编码 ]: 2909499000

[ 中文概述 ]:
2909499000 其他醚醇及其卤化、磺化、硝化或亚硝化衍生物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

D-松醇文献

Attenuation of oxidative stress and alteration of hepatic tissue ultrastructure by D-pinitol in streptozotocin-induced diabetic rats.

Free Radic. Res. 44(6) , 668-78, (2010)

The present study was aimed to investigate the effect of D-pinitol on hyperglycaemia mediated oxidative stress by analysing the hepatic antioxidant competence, pro-inflammatory cytokines and ultrastru...

The immunosuppressive effects of Agyrolobium roseum and pinitol in experimental animals.

Int. Immunopharmacol. 11(2) , 286-91, (2011)

Argyrolobium roseum (Papilionaceae) is a sexually reproducing, rare, annual herb that grows in tropical and sub-temperate tracts of the north-western Himalayan region of the Indian subcontinent. The p...

Determination of D-pinitol in carob syrup.

Int. J. Food Sci. Nutr. 62(6) , 572-6, (2011)

Carob syrup is a traditional product native to the Mediterranean region, containing a high concentration of sugar, phenolic compounds and minerals. d-pinitol is a bioactive component extracted from le...

更多文献

D-松醇相关知识

D-松醇的作用是什么？有哪些应用？

2022-04-19 17:24:01

标题：D-松醇的作用是什么？有哪些应用？　　背景及概述 [1-2]　　近几十年来，全球糖尿病患病数量急剧增加，已经成为继肿瘤、心脑血管疾病之后的第三大非传染性慢性疾病，严重影响人类的健康甚至危害生命，目前，我国已经成为糖尿病患者人数第二多的国家。　　目前常用的治疗糖尿病的药物主要有磺酰脲类药、双胍...