3-二乙胺基丙胺

3-二乙胺基丙胺用途

本品分子中由于含有两个活泼氢和一个对环氧树脂的固化反应有促进作用的叔胺基，可作为环氧树脂的固化剂。本品固化速度慢，使用寿命较长，适用于小型浇铸件、层压制品和黏合剂。用量6～12份，固化条件60℃/4h+120℃/1h。本品黏度低，使用方便，用本品固化的制品具有良好的电气性能和低温特性，热变形温度约100℃。本品还用作溶剂、萃取剂及有机合成中间体。

3-二乙胺基丙胺名称

[ CAS 号 ]:
104-78-9

[ 中文名 ]:
3-二乙胺基丙胺

[ 英文名 ]:
N,N-Diethylpropan-1,3-diamin

[中文别名 ]:

3-二乙氨基丙胺

[英文别名 ]:

EINECS 203-236-4
DIETHYLAMINO PROPYLAMINE
N,N-Diethylpropanediamine
3-dietgylpropanediamine
ATOFINA DEAPA
1,3-Propanediamine, N,N-diethyl-
N,N-Diethylpropan-1,3-diamin
N,N-diethylpropane-1,3-diamine
RARECHEM AL BW 0333
FENTAMINE DEAPA

3-二乙胺基丙胺物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
170.7±8.0 °C at 760 mmHg

[ 熔点 ]:
-60 °C

[ 分子式 ]:
C₇H₁₈N₂

[ 分子量 ]:
130.231

[ 闪点 ]:
58.9±0.0 °C

[ 精确质量 ]:
130.147003

[ PSA ]:
29.26000

[ LogP ]:
0.77

[ 外观性状 ]:
透明液体

[ 蒸汽密度 ]:
4.4 (vs air)

[ 蒸汽压 ]:
1.5±0.3 mmHg at 25°C

[ 折射率 ]:
1.451

[ 储存条件 ]:
包装完整、轻装轻卸,库房通风、远离明火、高温、与氧化剂?酸分开存放

[ 水溶解性 ]:
MISCIBLE

3-二乙胺基丙胺MSDS

3-二乙胺基丙胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX7350000

CHEMICAL NAME :: 1,3-Propanediamine, N,N-diethyl-

CAS REGISTRY NUMBER :: 104-78-9

BEILSTEIN REFERENCE NO. :: 0741879

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C7-H18-N2

MOLECULAR WEIGHT :: 130.27

WISWESSER LINE NOTATION :: Z3N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1410 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 2/27/1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 750 uL/kg

TOXIC EFFECTS :: Skin and Appendages - primary irritation (after topical exposure)

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84789 No. of Facilities: 201 (estimated) No. of Industries: 12 No. of Occupations: 15 No. of Employees: 2240 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84789 No. of Facilities: 17 (estimated) No. of Industries: 3 No. of Occupations: 3 No. of Employees: 460 (estimated) No. of Female Employees: 63 (estimated)

3-二乙胺基丙胺安全信息

[ 符号 ]:

GHS02, GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H226-H302 + H312-H314-H317

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R10;R21/22;R34;R43

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 2684 3/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
TX7350000

[ 包装等级 ]:
III

[ 危险类别 ]:
3

[ 海关编码 ]:
29212900

3-二乙胺基丙胺合成路线

3-二乙胺基丙胺上下游产品

3-二乙胺基丙胺上游产品

3-二乙胺基丙胺下游产品

3-二乙胺基丙胺制备

由丙烯腈与二乙胺加成后再经还原而得。将二乙胺加入反应釜，冷却至0℃，开启搅拌并滴加丙烯腈，温度逐渐自动升高到7℃。加完丙烯腈后，升温至45℃，继续搅拌反应2h，放置过夜。进行减压蒸馏，可得二乙氨基丙腈。将二乙氨基丙腈、反应介质甲醇胺饱和溶液和催化剂骨架镍加入高压釜内，通入氢气进行加氢还原反应，反应温度升至100℃，直至反应系统不再吸收氢为止。然后冷却放置，过滤回收催化剂，滤液加入蒸馏装置蒸出甲醇后进行分馏，即得成品。

3-二乙胺基丙胺海关

[ 海关编码 ]: 2921290000

[ 中文概述 ]:
2921290000. 其他无环多胺及其衍生物及它们的盐. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

3-二乙胺基丙胺文献

Amine-modified poly(vinyl alcohol)s as non-viral vectors for siRNA delivery: effects of the degree of amine substitution on physicochemical properties and knockdown efficiency.

Pharm. Res. 27(12) , 2670-82, (2010)

The objective of this study was to investigate how the degree of amine substitution of amine-modified poly(vinyl alcohol) (PVA) affects complexation of siRNA, protection of siRNA against degrading enz...

Low toxicity and long circulation time of polyampholyte-coated magnetic nanoparticles for blood pool contrast agents. Wang Qi, et al.

Sci. Rep. 5 , 7774, (2015)

Hyaluronated nanoparticles with pH-and enzyme-responsive drug release properties. Kim SW, et al.

Colloids Surf. B Biointerfaces 116 , 359-364, (2014)

更多文献