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1,1-二乙氧基乙烷

1,1-二乙氧基乙烷用途

用作重要的酒类添加剂，可作溶剂使用，也用于染料、塑料、香料的合成等

1,1-二乙氧基乙烷名称

[ CAS 号 ]:
105-57-7

[ 中文名 ]:
乙缩醛

[ 英文名 ]:
1,1-Diethoxyethane

[英文别名 ]:

Acetal diethylique
Decanal diethyl acetal
Decane,1,1-diethoxy
1,1-diethoxy-decane
Ethanal diethyl acetal
Decane,1-diethoxy
n-Decylaldehyd-diaethylacetal
Ethylidene diethyl ether
Acetaldehyde diethyl acetal
Diethoxy-1,1-ethane

1,1-二乙氧基乙烷物理化学性质

[ 密度 ]:
0.8±0.1 g/cm3

[ 沸点 ]:
103.6±0.0 °C at 760 mmHg

[ 熔点 ]:
-100 °C

[ 分子式 ]:
C₆H₁₄O₂

[ 分子量 ]:
118.174

[ 闪点 ]:
-21.1±0.0 °C

[ 精确质量 ]:
118.099380

[ PSA ]:
18.46000

[ LogP ]:
1.14

[ 外观性状 ]:
无色液体,辛辣,绿色木质的溶剂气味

[ 蒸汽密度 ]:
4.1 (vs air)

[ 蒸汽压 ]:
37.1±0.1 mmHg at 25°C

[ 折射率 ]:
1.389

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、酸类分开存放

[ 水溶解性 ]:
46 g/L (25 ºC)

1,1-二乙氧基乙烷MSDS

1,1-二乙氧基乙烷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB2800000

CHEMICAL NAME :: Acetaldehyde, diethyl acetal

CAS REGISTRY NUMBER :: 105-57-7

BEILSTEIN REFERENCE NO. :: 1098310

LAST UPDATED :: 199806

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C6-H14-O2

MOLECULAR WEIGHT :: 118.20

WISWESSER LINE NOTATION :: 2OY1&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,260,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: MDZEAK Medizin und Ernaehrung. (Stuttgart, Fed. Rep. Ger.) V.1-13, 1959-72. Discontinued. Volume(issue)/page/year: 8,244,1967

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,343,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 14CYAT "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63 Volume(issue)/page/year: 2,1982,1963

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 42(3),12,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3545 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 29,730,1932 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 01030 No. of Facilities: 1217 (estimated) No. of Industries: 5 No. of Occupations: 15 No. of Employees: 12775 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 01030 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 165 (estimated) No. of Female Employees: 83 (estimated)

1,1-二乙氧基乙烷安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H315-H319

[ 警示性声明 ]:
P210-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F:Flammable

[ 风险声明 (欧洲) ]:
R11;R36/38

[ 安全声明 (欧洲) ]:
S9-S16-S33

[ 危险品运输编码 ]:
UN 1088 3/PG 2

[ WGK德国 ]:
2

[ RTECS号 ]:
AB2800000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
29110000

1,1-二乙氧基乙烷合成路线

1,1-二乙氧基乙烷上下游产品

1,1-二乙氧基乙烷上游产品

1,1-二乙氧基乙烷下游产品

1,1-二乙氧基乙烷制备

1.由乙醛和乙醇在无水氯化钙和少量的无机酸存在下作用而得油状物，经无水碳酸钾干燥，再经分馏，收集101-103.5℃馏分，即为成品。

精制方法：主要杂质有乙醇、乙醛、三聚乙醛、过氧化物等。精制时可用碱性过氧化氢在40~45℃处理1小时。加入氯化钠到饱和，分出有机层。用无水碳酸钾干燥后过滤，加入金属钠蒸馏。也可以用碱性过氧化氢在65℃搅拌使醛氧化，然后用水洗涤，无水碳酸钾干燥，过滤，加金属钠蒸馏。

在控制温度为8℃的情况下，将新蒸出的乙醛缓慢加到盛有理论量的95%的乙醇和粒状无水氯化钙中，在少量无机酸作用下发生缩合反应。反应结束后，分出上层溶液，用少量水洗涤后，加入无水碳酸钾干燥脱水。然后于常压下蒸馏，收集101～103.5℃馏分，之后，将收集的馏分再重新蒸馏1～2次，即得成品。

1,1-二乙氧基乙烷海关

[ 海关编码 ]: 2911000000

[ 中文概述 ]:
2911000000 缩醛及半缩醛，不论是否含其他含氧基，及其卤化，磺化，硝化和亚硝化衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2911000000 acetals and hemiacetals, whether or not with other oxygen function, and their halogenated, sulphonated, nitrated or nitrosated derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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